Research activities

  • Isolation of compounds with pharmaceutical, cosmetic and nutritional interest from natural sources.
  • Search for new lead compounds of plant and marine origin from Greece, Mediterranean basin, Asia, S. America, Africa and New-Caledonia.
  • Chemical investigation of fungi.
  • Structural determination of natural products using up-to-date NMR techniques, Mass spectrometry and Molecular Modeling.
  • Receptor-ligand interaction using in silico techniques
  • Design and synthesis of new molecules with pharmacological interest (antitumor, antiviral, antibiotic, estrogen/anti-estrogen, CNS) based on a natural product skeleton; structure-activity relationships, optimization of lead compounds.
  • Development of CDK’s / GSK3 inhibitors
  • Development of SERMS (Selective Estrogen Receptor Modulators)
  • Research and development of PPAR ligans (obesity, antidiabetics)
  • Use and development of modern analytical chromatographic techniques for the isolation of bioactive natural compounds.
  • Treatment of agricultural wastes for the large scale production of high added value natural products.
  • Development of functional foods